A Randomized Placebo-Controlled Trial of Fluoxetine in Body Dysmorphic Disorder

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منابع مشابه

A randomized placebo-controlled trial of fluoxetine in body dysmorphic disorder.

BACKGROUND Research on the pharmacotherapy of body dysmorphic disorder (BDD), a common and often disabling disorder, is limited. Available data suggest that this disorder may respond to serotonin reuptake inhibitors. However, no placebo-controlled treatment studies of BDD have been published. METHODS Seventy-four patients with DSM-IV BDD or its delusional variant were enrolled and 67 were ran...

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Suicidality in a placebo-controlled fluoxetine study of body dysmorphic disorder.

Serotonin reuptake inhibitors are considered the first-line medication for body dysmorphic disorder (BDD). The relationship between serotonin reuptake inhibitor treatment and suicidality in BDD has been only minimally studied, despite high suicidality rates in BDD. Sixty-seven adults with the Diagnostic and Statistical Manual of Mental Disorders edition IV BDD participated in a 12-week randomiz...

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Placebo-controlled study of pimozide augmentation of fluoxetine in body dysmorphic disorder.

OBJECTIVE Although body dysmorphic disorder often responds to serotonin reuptake inhibitors (SRIs), most patients do not respond or respond only partially. However, placebo-controlled studies of augmentation of SRIs have not been done. Furthermore, although 40%-50% of patients are delusional, studies of antipsychotic medications have not been done. METHOD Twenty-eight patients with body dysmo...

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A Pilot Randomized Controlled Trial of Cognitive-Behavioral Therapy for Adolescents With Body Dysmorphic Disorder.

OBJECTIVE Body dysmorphic disorder (BDD) typically starts in adolescence, but evidence-based treatments are yet to be developed and formally evaluated in this age group. We designed an age-appropriate cognitive-behavioral therapy (CBT) protocol for adolescents with BDD and evaluated its acceptability and efficacy in a pilot randomized controlled trial. METHOD Thirty adolescents aged 12 to 18 ...

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Fluoxetine was safe and effective for body dysmorphic disorder.

Patients 74 patients who had DSM-IV confirmed BDD with or without a delusional disorder for ≥ 6 months, were 18–65 years of age, scored ≥ 24 on the Yale-Brown Obsessive Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS), and scored at least moderate on the Clinical Global Impression scale for BDD (BDD-CGI). Exclusion criteria included psychotic disorder not attributable to delus...

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ژورنال

عنوان ژورنال: Archives of General Psychiatry

سال: 2002

ISSN: 0003-990X

DOI: 10.1001/archpsyc.59.4.381